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Every day it seems that we’re learning more about the different compounds inside cannabis and what makes them so unique. As the popularity of cannabis increases worldwide, so too does the amount of research time scientists spend trying to unlock all of its secrets. For the last hundred years or so, cannabis was looked down on as a narcotic with very little therapeutic value, but that’s all changed in the last decade as countries around the world start taking a proactive approach to this natural compound. One study that has gotten many people talking recently concluded that a non-cannabinoid, non-psychotropic flavonoid, FBL-03G, could have the potential to treat pancreatic cancer. The study was conducted by researchers at Harvard Medical School and the Dana Farber Cancer Institute. The study utilized animal models to assess the impact of FBL-03G, a flavonoid that is derived from cannabis sativa, on the progression of tumors. The researchers looked at FBL-03G’s ability to reduce the size of tumors in conjunction with other traditional cancer treatments, including radiation. Researches used a combination of different treatments using FBL-03G as an immunoadjuvant; in vitro studies were carried out with and without the assistance of radiotherapy. The FBL-03G flavonoid was delivered utilizing smart radiotherapy biomaterials. Currently, on average, 60,000 people will be diagnosed with pancreatic cancer every year in the United States. The survival rate for people that are unfortunate enough to be diagnosed with advanced pancreatic cancer is approximately five years. The traditional treatment for pancreatic cancer includes chemotherapy, radiation, immunotherapy, and surgery, but due to pancreatic cancer’s aggressive nature, all options have limited success. What Are Cannabis Flavonoids? Flavonoids are found in a variety of different plants, vegetables, and fruits. The flavonoids that are exclusive to cannabis are known as cannaflavins. They assist the plant in attracting birds, insects, and bees that enable the plant to pollinate while protecting the plant from disease and other insects that may attack it. We’re learning more about flavonoids and the other compounds which make up the cannabis plant every day but much more research is needed before we unlock the full potential of cannabis. Cannabis Flavonoids Conclusion The study, which was published in Frontiers of Oncology, involved conducting repeated experiments which showed that many animals had an increased survival rate from pancreatic cancer compared to the animals in the control groups. A statement by the people conducting the study stated, “While ongoing studies are in progress to address the specific mechanism for this immunotherapy potential of this cannabis derivative, the possibility of leveraging such a therapy approach to treat metastasis or increase survival is significant, given that most pancreatic cancer patients are diagnosed already with metastatic disease, with limited treatment options.” “The results highlight the potential of using non-cannabinoid, non-psychoactive derivatives of cannabis for such treatment. Further work to optimize therapeutic efficacy for such cannabis derivatives and evaluate toxicity could set the stage for clinical translation.” “The FBL-03G results reveal a new potential non-cannabinoid cannabis derivative with major potential for consideration in further investigations in the treatment of pancreatic cancer, where new therapy options are urgently needed.” While these initial results are encouraging, researchers still have a long way to go before they fully understand cannabis and the compounds which make up this plant. If you’re currently taking any medication and considering trying cannabis, always speak to your doctor or healthcare provider first as cannabis can interfere with how our bodies process some medication. If you would like to learn more about cannabis or enjoyed the article, please don’t hesitate to comment below, share the article, or contact us directly. Cheers, -APN
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